exRNAdisease

Entry Detail

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General Information

Database ID: exR0755502 RNA Name: AFF1 RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 86935002 End Site(bp): 87141054 External Links: ENSG00000172493

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AP1G1 chr16 71729000 71809201 - TMBIM6 chr12 49707725 49764934 + UBALD2 chr17 76265348 76271298 + KIF1C chr17 4997950 5028401 + ERAL1 chr17 28855010 28861061 + HNRNPM chr19 8444767 8489114 + DUSP5 chr10 110497907 110511533 + VPS13A chr9 77177445 77421537 + RAB5C chr17 42124976 42155044 - RAVER2 chr1 64745095 64833232 + RSU1 chr10 16590611 16817463 - DNAJC5 chr20 63895126 63936031 + RHEB chr7 151466012 151520120 - TSR1 chr17 2322396 2336657 - CHD8 chr14 21385194 21456126 - UNC13D chr17 75827225 75844717 - MCM2 chr3 127598410 127622436 + RANBP2 chr2 108719482 108785809 + ACTG1 chr17 81509971 81523847 - PRDX6 chr1 173477330 173488815 + BAZ1B chr7 73440406 73522293 - ABI1 chr10 26746593 26861087 - KRAS chr12 25205246 25250936 - STRBP chr9 123109500 123268586 - CC2D1A chr19 13906201 13930879 + COPS8 chr2 237085882 237100474 + DEDD chr1 161120974 161132688 - SSRP1 chr11 57325986 57335892 - CASP8 chr2 201233443 201287711 + TMEM237 chr2 201620184 201643570 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC025181.2 chr5 32174471 32175272 + MAPKAPK5-AS1 chr12 111839764 111842902 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.