exRNAdisease

Entry Detail

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General Information

Database ID: exR0755504 RNA Name: AFF3 RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 99545419 End Site(bp): 100192428 External Links: ENSG00000144218

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC135050.2 chr16 31083439 31094956 - ALG8 chr11 78100936 78139653 - CCNF chr16 2429394 2458854 + CEP170 chr1 243124428 243255348 - CERS5 chr12 50129289 50167533 - FBXL19 chr16 30923055 30948783 + FOXP2 chr7 114086327 114693772 + GNB2 chr7 100673567 100679174 + HDDC3 chr15 90929964 90935196 - HMGA2 chr12 65824131 65966295 + HS6ST1 chr2 128236716 128318868 - INTS7 chr1 211940399 212035557 - JRK chr8 142657460 142681968 - MECOM chr3 169083499 169663775 - NISCH chr3 52455118 52493068 + SIPA1L3 chr19 37907208 38208369 + TMEM250 chr9 136114581 136118875 - VKORC1 chr16 31090842 31095980 - ZBED4 chr22 49853844 49890080 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-33a-5p chr22 41900949 41900969 + hsa-miR-520d-5p chr19 53720111 53720130 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026471.1 chr16 31456711 31459736 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.