exRNAdisease

Entry Detail

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General Information

Database ID: exR0755508 RNA Name: AFTPH RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 64524305 End Site(bp): 64593005 External Links: ENSG00000119844

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand BID chr22 17734138 17774770 - YWHAQ chr2 9583967 9630997 - CLEC2D chr12 9664969 9699553 + NAP1L1 chr12 76036585 76084958 - DTYMK chr2 241675747 241686944 - TWSG1 chr18 9334767 9402420 + TUBA1B chr12 49127782 49131397 - LAMC1 chr1 183023420 183145592 + BIRC2 chr11 102347211 102378670 + CUL3 chr2 224470150 224585397 - PGK1 chrX 77910739 78129295 + HLA-A chr6 29941260 29945884 + HEXA chr15 72340919 72376476 - STRN4 chr19 46719511 46746994 - RPUSD4 chr11 126202096 126211692 - HLA-F chr6 29722775 29738528 + BRPF3 chr6 36196744 36232790 + CD48 chr1 160678746 160711831 - ATP5MG chr11 118401606 118431496 + LCP1 chr13 46125920 46211871 - ATP8B2 chr1 154325553 154351304 + NCL chr2 231453531 231483641 - AKIRIN2 chr6 87674860 87702233 - HNRNPU chr1 244840638 244864560 - HDAC2 chr6 113933028 114011308 - PHF20 chr20 35771974 35950370 + RPL32 chr3 12834485 12841582 - MRPL4 chr19 10251901 10260055 + RPL27 chr17 42998273 43002959 + YWHAH chr22 31944522 31957603 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC01405 chr12 110934590 110959093 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.