exRNAdisease

Entry Detail

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General Information

Database ID: exR0755515 RNA Name: AGFG2 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 100539203 End Site(bp): 100568220 External Links: ENSG00000106351

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HK1 chr10 69269984 69401884 + DUSP2 chr2 96143169 96145440 - HMGA1 chr6 34236873 34246231 + ADCY3 chr2 24819169 24919839 - BLCAP chr20 37492472 37527931 - KCNQ5 chr6 72621792 73198851 + LASP1 chr17 38869859 38921770 + RPS5 chr19 58386400 58394806 + CORO1B chr11 67435510 67443821 - RBM42 chr19 35629030 35637686 + DDX5 chr17 64498254 64508199 - RPS19 chr19 41860255 41872925 + REEP5 chr5 112876385 112922289 - HLA-A chr6 29941260 29945884 + VPS4A chr16 69311350 69326939 + SLC12A8 chr3 125082636 125212864 - ZFP36L1 chr14 68787660 68796253 - HLA-E chr6 30489509 30494194 + ARID3A chr19 925781 975939 + RPL13 chr16 89560657 89566828 + PTPRCAP chr11 67435510 67437682 - SOX13 chr1 204073115 204127743 + NMT1 chr17 45051610 45109016 + CRKL chr22 20917407 20953747 + INAFM2 chr15 40323692 40326715 + CDK1 chr10 60778331 60794852 + TUBA1B chr12 49127782 49131397 - BASP1 chr5 17065598 17276843 + TMEM54 chr1 32894594 32901438 - TPT1 chr13 45333471 45341370 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC009065.3 chr16 2091436 2095433 + TMEM147-AS1 chr19 35540738 35546029 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.