exRNAdisease

Entry Detail

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General Information

Database ID: exR0755517 RNA Name: AGL RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 99850361 End Site(bp): 99924023 External Links: ENSG00000162688

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand FSD1 chr19 4304598 4323843 + ATP5F1B chr12 56638175 56645984 - MRPL16 chr11 59806140 59810778 - CTPS1 chr1 40979688 41012565 + MARCKSL1 chr1 32333839 32336233 - ERCC6 chr10 49454470 49539538 - APP chr21 25880550 26171128 - CRLS1 chr20 6006093 6040053 + NAT10 chr11 34105617 34147670 + EEF1A1 chr6 73515750 73523797 - PTOV1 chr19 49850735 49860744 + NUCKS1 chr1 205712822 205750182 - KLHL15 chrX 23983720 24027186 - PPIA chr7 44796680 44824564 + RPS8 chr1 44775251 44778779 + POLD3 chr11 74493851 74669117 + ANXA7 chr10 73375101 73414076 - TBKBP1 chr17 47694081 47712050 + CARD10 chr22 37490362 37519542 - IQSEC1 chr3 12897043 13283281 - BEX4 chrX 103215108 103217246 + MRPL13 chr8 120380761 120445402 - CIAPIN1 chr16 57428187 57447420 - MIGA2 chr9 129036621 129072082 + KIF3C chr2 25926598 25982749 - DTL chr1 212035553 212107400 + KHDRBS1 chr1 32013868 32060850 + UHMK1 chr1 162497251 162529631 + AURKAIP1 chr1 1373730 1375495 - PARP1 chr1 226360691 226408093 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302b-3p chr4 112648489 112648511 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC00910 chr17 43338741 43389199 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.