exRNAdisease

Entry Detail

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General Information

Database ID: exR0755523 RNA Name: AGPAT1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 32168212 End Site(bp): 32178096 External Links: ENSG00000204310

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand NAP1L3 chrX 93670930 93673578 - UBC chr12 124911604 124917368 - ENO1 chr1 8861000 8879190 - TRIM71 chr3 32817997 32897824 + NEMP1 chr12 57055643 57088063 - DBN1 chr5 177456608 177474401 - DAG1 chr3 49468703 49535618 + ABHD17C chr15 80679684 80755621 + ATR chr3 142449007 142578733 - MT-ND1 chrMT 3307 4262 + SNRNP200 chr2 96274338 96321271 - TMPO chr12 98515512 98550379 + DHFR chr5 80626226 80654983 - PAK6 chr15 40217428 40277487 + NEK6 chr9 124257606 124353307 + APP chr21 25880550 26171128 - GMPS chr3 155870650 155944020 + ACTG1 chr17 81509971 81523847 - MFSD12 chr19 3538261 3574290 - RPS3 chr11 75399515 75422280 + RAI1 chr17 17681458 17811453 + CBX1 chr17 48070052 48101478 - SDHC chr1 161314257 161375340 + AL121753.1 chr20 35267885 35280043 - EDC4 chr16 67873052 67884499 + PTPN12 chr7 77537295 77640069 + COX7A2L chr2 42333546 42425088 - RPL31 chr2 101002229 101024032 + ELF1 chr13 40931924 41061440 - SIX4 chr14 60709539 60724351 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC040162.3 chr16 67882461 67886367 + GATA3-AS1 chr10 8050450 8053484 - OIP5-AS1 chr15 41283990 41309737 + SNHG16 chr17 76557764 76565348 + XIST chrX 73820649 73852723 - ZNF436-AS1 chr1 23368997 23371839 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.