exRNAdisease

Entry Detail

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General Information

Database ID: exR0755524 RNA Name: AGPAT3 RNA Type: mRNA Chromosome: chr21 Starnd: + Coordinate: Start Site(bp): 43865223 End Site(bp): 43987592 External Links: ENSG00000160216

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TUBB chr6 30720352 30725426 + WDR54 chr2 74421678 74425755 + RPLP1 chr15 69452814 69456205 + CARD9 chr9 136361903 136373681 - VAPB chr20 58389229 58451101 + IPO9 chr1 201829149 201884291 + KCTD3 chr1 215567304 215621807 + IMP3 chr15 75639085 75648706 - CLN3 chr16 28474111 28495575 - OSGEP chr14 20446401 20455089 - PPRC1 chr10 102132994 102150333 + CKLF chr16 66552563 66566251 + PDIA4 chr7 149003062 149028662 - RBM15 chr1 110338506 110346681 + RPL27A chr11 8682788 8714759 + ANKRD28 chr3 15667236 15859771 - HLA-B chr6 31269491 31357188 - BHLHE40 chr3 4979437 4985323 + SQSTM1 chr5 179806398 179838078 + RER1 chr1 2391775 2405442 + LAMC1 chr1 183023420 183145592 + RUNDC1 chr17 42980565 42993690 + POMK chr8 43093506 43123434 + GON4L chr1 155749662 155859400 - ACAP3 chr1 1292390 1309609 - DTNBP1 chr6 15522801 15663058 - PIK3R2 chr19 18153163 18170532 + ACIN1 chr14 23058564 23095614 - AC007192.1 chr19 18153158 18178117 + SPC24 chr19 11131520 11155808 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL049840.4 chr14 103694516 103695050 - AC010326.4 chr19 57867038 57868172 - AL355075.4 chr14 20343048 20343685 - LINC00665 chr19 36313067 36331770 - LINC01754 chr20 47391925 47412327 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.