exRNAdisease

Entry Detail

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General Information

Database ID: exR0755528 RNA Name: AGTPBP1 RNA Type: mRNA Chromosome: chr9 Starnd: - Coordinate: Start Site(bp): 85546539 End Site(bp): 85742029 External Links: ENSG00000135049

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand COL5A1 chr9 134641803 134844843 + EEF2 chr19 3976056 3985463 - EPOP chr17 38671703 38674957 - CCDC88C chr14 91271323 91417844 - TADA2B chr4 7041899 7057952 + HNRNPK chr9 83968083 83980616 - RPS27A chr2 55231903 55235853 + PSMD3 chr17 39980807 39997959 + VAMP3 chr1 7771296 7781432 + GPRC5B chr16 19856691 19886167 - CCDC189 chr16 30757423 30762221 - CCAR2 chr8 22604632 22621514 + CAND2 chr3 12796472 12871916 + DNAJB6 chr7 157335381 157417439 + TPT1 chr13 45333471 45341370 - METTL7A chr12 50923472 50932510 + PLXNA3 chrX 154458281 154477779 + SMARCD1 chr12 50085200 50100707 + ST13 chr22 40824535 40856639 - U2SURP chr3 142964497 143060725 + ZNF234 chr19 44141554 44160313 + ABHD14B chr3 51968510 51983409 - TYMS chr18 657653 673578 + GATAD2B chr1 153789030 153923360 - STAT1 chr2 190908460 191020960 - RANBP1 chr22 20115938 20127355 + VTI1B chr14 67647085 67674820 - IRF4 chr6 391752 411443 + C1orf210 chr1 43281877 43285617 - CALM3 chr19 46601074 46610782 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand PDCD4-AS1 chr10 110869868 110872233 - ZFAS1 chr20 49278178 49299600 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.