exRNAdisease

Entry Detail

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General Information

Database ID: exR0755536 RNA Name: AHNAK RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 62433542 End Site(bp): 62556235 External Links: ENSG00000124942

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand SRRM2 chr16 2752626 2772538 + C15orf39 chr15 75195643 75212169 + DGKI chr7 137381037 137847092 - LRRC8A chr9 128882112 128918039 + PPP1R8 chr1 27830782 27851676 + COMT chr22 19941733 19969975 + SLC16A1 chr1 112911847 112957013 - RBM33 chr7 155644451 155781485 + PSMD8 chr19 38374536 38383824 + PSMB1 chr6 170535120 170553307 - DNMT3A chr2 25227855 25342590 - PABPC3 chr13 25095868 25099254 + TOR1AIP2 chr1 179839967 179877803 - APP chr21 25880550 26171128 - MPZL1 chr1 167721192 167791919 + DCAF8 chr1 160215715 160262549 - FBXO31 chr16 87326987 87392142 - SORL1 chr11 121452314 121633763 + RABEP1 chr17 5282265 5386340 + ARL2BP chr16 57245259 57253635 + HUWE1 chrX 53532096 53686728 - RACK1 chr5 181236897 181248096 - KDM6A chrX 44873177 45112602 + CCNG2 chr4 77157207 77433388 + TMEM132A chr11 60924463 60937159 + PPP6R1 chr19 55229779 55259017 - R3HCC1 chr8 23270120 23296279 + TTC38 chr22 46267961 46294008 + MFN2 chr1 11980181 12013514 + MORF4L2 chrX 103675496 103688158 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC010327.5 chr19 55216660 55221616 + AD000090.1 chr19 35557956 35581954 + AL139385.1 chr13 110613082 110616353 - LINC00174 chr7 66376044 66493566 - RMRP chr9 35657751 35658018 - XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.