exRNAdisease

Entry Detail

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General Information

Database ID: exR0755538 RNA Name: AHR RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 16916359 End Site(bp): 17346152 External Links: ENSG00000106546

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKR1A1 chr1 45550543 45570049 + AP3B1 chr5 78000525 78294755 - CAPRIN1 chr11 34051731 34102610 + CCDC91 chr12 28133249 28581511 + CNN3 chr1 94896949 94927223 - COMMD1 chr2 61888724 62147247 + DCAF6 chr1 167935783 168075843 + FLT4 chr5 180601506 180649624 - GAPDH chr12 6534512 6538374 + HMGB2 chr4 173331376 173334432 - LGALS9 chr17 27629798 27649560 + MED28 chr4 17614641 17634105 + NAGK chr2 71064344 71079808 + NOP53 chr19 47745546 47757058 + PTBP1 chr19 797075 812327 + RFTN1 chr3 16313574 16514026 - RPS23 chr5 82273320 82278396 - RPS5 chr19 58386400 58394806 + SLC2A3 chr12 7919230 7936187 - SRF chr6 43171269 43181506 + SRP9 chr1 225777813 225790468 + USP53 chr4 119212587 119295517 + YIPF6 chrX 68498562 68537282 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC019117.3 chr7 17374867 17467256 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.