exRNAdisease

Entry Detail

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General Information

Database ID: exR0755541 RNA Name: AICDA RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 8602170 End Site(bp): 8612867 External Links: ENSG00000111732

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ERCC5 chr13 102807146 102876001 + UBE2Z chr17 48908407 48929056 + TAPBP chr6 33299694 33314387 - ALDH9A1 chr1 165662216 165698863 - ITM2C chr2 230864639 230879248 + ACTR1B chr2 97655939 97664044 - LGMN chr14 92703807 92748679 - ABL1 chr9 130713016 130887675 + AC027644.4 chr7 66628958 66811189 + RPL30 chr8 98024851 98046469 - ATP5MG chr11 118401606 118431496 + POMT2 chr14 77274956 77320884 - RPS16 chr19 39433137 39435949 - SMUG1 chr12 54121277 54189008 - UBA2 chr19 34428352 34471251 + DCAF1 chr3 51395867 51500002 - MT-ND4 chrMT 10760 12137 + NADSYN1 chr11 71453109 71524107 + AP001781.2 chr11 111786286 111879425 - GAPDH chr12 6534512 6538374 + NACA2 chr17 61590421 61591219 - TOP2A chr17 40388525 40417896 - GAS2L3 chr12 100573683 100628288 + POLG2 chr17 64477785 64497054 - ATP5F1C chr10 7788147 7807815 + RPL8 chr8 144789765 144792587 - MTRNR2L8 chr11 10507894 10509186 - OVOL1 chr11 65787063 65797214 + RABGEF1 chr7 66682164 66811464 + SLC25A3 chr12 98593591 98606379 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand LINC02154 chrX 13266048 13303452 - MIR155HG chr21 25561909 25575168 + TSPOAP1-AS1 chr17 58324472 58415766 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.