exRNAdisease

Entry Detail

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General Information

Database ID: exR0755543 RNA Name: AIF1 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 31615217 End Site(bp): 31617021 External Links: ENSG00000204472

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + AC008403.1 chr19 48465837 48472431 + ANP32B chr9 97983341 98015943 + CCT7 chr2 73233420 73253021 + COX7A2L chr2 42333546 42425088 - CYTH2 chr19 48469208 48482314 + DAXX chr6 33318558 33323016 - GCK chr7 44143213 44198170 - IAH1 chr2 9473658 9496543 + LEF1 chr4 108047545 108168956 - NDUFA4 chr7 10931943 10940153 - NDUFB9 chr8 124539101 124580648 + RACK1 chr5 181236897 181248096 - RBPJ chr4 26163455 26435131 + RPL27A chr11 8682788 8714759 + RPL37A chr2 216498825 216579180 + RPLP2 chr11 809965 812880 + SIPA1L3 chr19 37907208 38208369 + SRP9 chr1 225777813 225790468 + TCF15 chr20 603797 610398 - TUBA1A chr12 49184795 49189080 - UQCC3 chr11 62670273 62673686 + ZNF322 chr6 26634383 26659752 - miRNA targets: NA circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.