exRNAdisease

Entry Detail

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General Information

Database ID: exR0755546 RNA Name: AIFM2 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 70098223 End Site(bp): 70132934 External Links: ENSG00000042286

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + AC105052.1 chr7 102582523 102642869 - BTF3 chr5 73498408 73505635 + DCP2 chr5 112976702 113022195 + DNM2 chr19 10718079 10833488 + FOXM1 chr12 2857681 2877155 - FTL chr19 48965309 48966879 + GPX4 chr19 1103926 1106791 + HMGN1 chr21 39342315 39349647 - MT-CO3 chrMT 9207 9990 + MUTYH chr1 45329163 45340893 - PAFAH1B1 chr17 2593210 2685615 + PGK1 chrX 77910739 78129295 + PLEKHM2 chr1 15684320 15734769 + RASA4 chr7 102573807 102616757 - RPL13 chr16 89560657 89566828 + RPLP2 chr11 809965 812880 + TPT1 chr13 45333471 45341370 - TYSND1 chr10 70137981 70146700 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.