exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755550 RNA Name: AIMP2 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 6009255 End Site(bp): 6023834 External Links: ENSG00000106305

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026954.2 chr17 7312661 7319174 - RPL36 chr19 5674947 5691875 + TFG chr3 100709331 100748964 + CCDC163 chr1 45493866 45500079 - RPL19 chr17 39200283 39204732 + PAICS chr4 56435741 56464579 + CDK16 chrX 47217860 47229997 + AC139530.2 chr17 81703371 81720539 + IMP3 chr15 75639085 75648706 - EPN1 chr19 55675226 55709858 + NDUFV1 chr11 67605653 67612554 + BFAR chr16 14632931 14669236 + PRR13 chr12 53441678 53446645 + NMT1 chr17 45051610 45109016 + EEF2 chr19 3976056 3985463 - FTSJ3 chr17 63819433 63830012 - CYP51A1 chr7 92112153 92134803 - BZW1 chr2 200810594 200827338 + MIF chr22 23894383 23895227 + MCL1 chr1 150574551 150579738 - DYNLL1 chr12 120469850 120498493 + SNX30 chr9 112750760 112881671 + SMO chr7 129188633 129213545 + GLUL chr1 182381704 182392206 - KDM4B chr19 4969113 5153598 + FBRS chr16 30658431 30670810 + RNASEK-C17orf49 chr17 7012635 7017520 + NFE2L1 chr17 48048329 48061545 + CTSB chr8 11842524 11869448 - CTNNBL1 chr20 37693955 37872129 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + ATP2B1-AS1 chr12 89708959 89712590 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + TPT1-AS1 chr13 45341345 45417975 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.