exRNAdisease

Entry Detail

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General Information

Database ID: exR0755557 RNA Name: AK6 RNA Type: mRNA Chromosome: chr5 Starnd: - Coordinate: Start Site(bp): 69350984 End Site(bp): 69370013 External Links: ENSG00000085231

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AL513165.2 chr9 37512547 37592469 - BICC1 chr10 58512872 58831435 + FBXO10 chr9 37510892 37576380 - FOXP4 chr6 41546426 41602384 + GLRX3 chr10 130136391 130184521 + KPNA1 chr3 122421902 122514945 - LTV1 chr6 143843338 143863812 + NFS1 chr20 35668052 35699355 - PPP2R1B chr11 111726908 111766389 - RAB12 chr18 8609437 8639382 + RAB1A chr2 65070696 65130331 - RANBP9 chr6 13621498 13711835 - RBMX chrX 136848004 136880764 - SNRPD2 chr19 45687454 45692569 - TAF9 chr5 69364743 69370013 - TJP1 chr15 29699367 29968865 - USP1 chr1 62436297 62451804 + WDFY4 chr10 48684876 48982956 + WDR7 chr18 56651343 57036606 + ZFAND5 chr9 72351413 72365235 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AL138689.2 chr13 106491147 106521630 + IQCH-AS1 chr15 67290636 67521844 - SNHG3 chr1 28505980 28510892 + WDR7-OT1 chr18 57027832 57038845 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.