exRNAdisease

Entry Detail

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General Information

Database ID: exR0755563 RNA Name: AKAP12 RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 151239967 End Site(bp): 151358559 External Links: ENSG00000131016

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand MAVS chr20 3846799 3876123 + CALM1 chr14 90396502 90408268 + AP1B1 chr22 29327680 29423179 - SLC25A3 chr12 98593591 98606379 + MEPCE chr7 100428790 100434118 + PLCXD1 chrX 276322 303356 + CEP68 chr2 65056366 65087004 + ARNT chr1 150809713 150876708 - SLC3A2 chr11 62856102 62888875 + PAQR3 chr4 78887127 78939438 - RAB3GAP1 chr2 135052265 135176394 + ACTG1 chr17 81509971 81523847 - TMBIM6 chr12 49707725 49764934 + ZNF646 chr16 31074422 31084196 + PSME4 chr2 53864069 53970993 - TAF10 chr11 6606294 6612539 - LAMP1 chr13 113297239 113323672 + HNRNPF chr10 43385617 43409166 - ADGRG6 chr6 142301854 142446266 + SNX3 chr6 108211222 108261246 - GPHN chr14 66507407 67181803 + PARN chr16 14435700 14632728 - UNC45A chr15 90930180 90954093 + HERC2 chr15 28111040 28322172 - B4GALT4 chr3 119211732 119240946 - DSTN chr20 17570075 17609919 + ADGRL1 chr19 14147743 14206187 - MTHFD2 chr2 74198610 74217565 + SC5D chr11 121292681 121313410 + STT3B chr3 31532638 31637616 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC091564.7 chr11 6610883 6616594 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.