exRNAdisease

Entry Detail

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General Information

Database ID: exR0755571 RNA Name: AKAP8 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 15353385 End Site(bp): 15379798 External Links: ENSG00000105127

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANAPC7 chr12 110372900 110403730 - SHQ1 chr3 72749277 72861914 - ZNF500 chr16 4748239 4767624 - UBN1 chr16 4846665 4882401 + CALR chr19 12938578 12944489 + ICE2 chr15 60419609 60479160 - L1TD1 chr1 62194849 62212328 + TRIP12 chr2 229763838 229923239 - ZNF43 chr19 21804949 21852125 - GMPS chr3 155870650 155944020 + ABCC1 chr16 15949577 16143074 + RPL36A-HNRNPH2 chrX 101391011 101412297 + BAMBI chr10 28677510 28682932 + NACA2 chr17 61590421 61591219 - ZZEF1 chr17 4004445 4143030 - PPP1R12C chr19 55090914 55117637 - TLE3 chr15 70047790 70098176 - NCL chr2 231453531 231483641 - DCAF10 chr9 37800554 37867666 + MIXL1 chr1 226223618 226227054 + NAT10 chr11 34105617 34147670 + ALDOA chr16 30064164 30070457 + MON1B chr16 77190835 77202398 + TIMMDC1 chr3 119498547 119525090 + SH3PXD2A chr10 103594027 103855543 - ATF6B chr6 32115264 32128253 - CDK7 chr5 69234795 69277430 + RIPOR1 chr16 67518418 67546788 + NPC2 chr14 74476192 74494177 - CACNG6 chr19 53992288 54012669 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL355075.4 chr14 20343048 20343685 - LINC01248 chr2 5602505 5691488 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.