exRNAdisease

Entry Detail

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General Information

Database ID: exR0755574 RNA Name: AKIP1 RNA Type: mRNA Chromosome: chr11 Starnd: + Coordinate: Start Site(bp): 8911139 End Site(bp): 8920084 External Links: ENSG00000166452

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CBX3 chr7 26201162 26213607 + FSCN1 chr7 5592816 5606655 + MDM2 chr12 68808177 68850686 + OAS3 chr12 112938444 112973251 + COPS7B chr2 231781671 231809254 + EIF1 chr17 41688885 41692668 + MRPL49 chr11 65122183 65127371 + SLC2A1 chr1 42925375 42958868 - B2M chr15 44711487 44718877 + NIPSNAP1 chr22 29554808 29581327 - AK4 chr1 65147549 65232145 + SLC25A6 chrX 1386152 1392113 - DHX15 chr4 24517441 24584554 - VLDLR chr9 2621787 2660056 + AL136454.1 chr1 192716132 192716653 + TXNL1 chr18 56597209 56651600 - CHKB-CPT1B chr22 50568869 50582965 - KRT7 chr12 52232520 52252186 + TAGLN2 chr1 159918107 159925732 - CHMP1A chr16 89644435 89657721 - FP565260.6 chr21 5155499 5165472 - FP565260.2 chr21 5116343 5133805 - OST4 chr2 27070472 27071654 - TSTD2 chr9 97600080 97633368 - PSMA5 chr1 109399042 109426448 - PPP2R1A chr19 52190048 52229518 + IL21R chr16 27402174 27452042 + THOC5 chr22 29505879 29555216 - GPSM3 chr6 32190766 32195523 - MAT2A chr2 85539168 85545281 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand DANCR chr4 52712404 52720351 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.