exRNAdisease

Entry Detail

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General Information

Database ID: exR0755584 RNA Name: AKR7A2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 19303965 End Site(bp): 19312146 External Links: ENSG00000053371

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand HSD17B12 chr11 43680680 43856617 + PRELID1 chr5 177303799 177306949 + SAMD11 chr1 923928 944581 + FEM1A chr19 4791734 4801273 + AC073508.2 chr17 40627356 40665141 - MCAM chr11 119308529 119321521 - HSPA1B chr6 31827738 31830254 + SHB chr9 37915898 38069227 - VIM chr10 17228241 17237593 + GDPD3 chr16 30104810 30113537 - ELFN2 chr22 37367960 37427479 - DDX3Y chrY 12904108 12920478 + CD74 chr5 150400041 150412929 - HNRNPA2B1 chr7 26173057 26201529 - ATP1A1 chr1 116372668 116410261 + MIF chr22 23894383 23895227 + NPTX1 chr17 80466834 80477843 - SMARCE1 chr17 40624962 40648654 - DDB1 chr11 61299451 61342596 - TRIO chr5 14143342 14532128 + RPLP1 chr15 69452814 69456205 + CHMP2A chr19 58551566 58555105 - HMGA1 chr6 34236873 34246231 + CAD chr2 27217369 27243943 + ID1 chr20 31605283 31606515 + NR1D2 chr3 23945286 23980617 + RPL10 chrX 154389955 154409168 + RASSF3 chr12 64507001 64697564 + MESD chr15 80946289 80989828 - RPS8 chr1 44775251 44778779 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AP000317.2 chr21 34073592 34360033 + MALAT1 chr11 65497688 65506516 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.