exRNAdisease

Entry Detail

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General Information

Database ID: exR0755586 RNA Name: AKT1S1 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 49869033 End Site(bp): 49878459 External Links: ENSG00000204673

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand YIPF3 chr6 43511832 43516985 - FOXRED2 chr22 36487190 36507101 - FAM86C1 chr11 71787510 71801237 + BABAM2 chr2 27889941 28338901 + PABPN1 chr14 23321289 23326185 + BBS10 chr12 76344474 76348415 - ESYT1 chr12 56118250 56144671 + ZNF585A chr19 37106734 37172741 - SEC62 chr3 169966635 169998373 + EEF1G chr11 62559596 62574086 - SEPHS1 chr10 13317428 13348298 - STAG3 chr7 100177563 100221488 + CBX1 chr17 48070052 48101478 - KIAA2013 chr1 11919591 11926428 - IRF2BP2 chr1 234604269 234609525 - NOMO3 chr16 16232528 16294811 + KAT7 chr17 49788681 49835026 + ZFP36L1 chr14 68787660 68796253 - PODXL chr7 131500262 131558217 - CRABP2 chr1 156699606 156705816 - PILRB chr7 100352176 100367733 + AGO2 chr8 140520156 140635633 - DPY19L1 chr7 34928876 35038271 - ATF5 chr19 49928702 49933935 + ID1 chr20 31605283 31606515 + MYL6 chr12 56158161 56163496 + TMEM256-PLSCR3 chr17 7389734 7404097 - SLC6A6 chr3 14402576 14489349 + NLRX1 chr11 119166568 119184016 + HNRNPUL1 chr19 41262496 41307787 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC079949.1 chr12 127142029 127146532 - AP001626.1 chr21 42648271 42651244 - HCG18 chr6 30286690 30327382 - SLX1A-SULT1A3 chr16 30193892 30204310 + STAG3L5P-PVRIG2P-PILRB chr7 100336104 100367831 + XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.