exRNAdisease

Entry Detail

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General Information

Database ID: exR0755590 RNA Name: AL139011.2 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 160216800 End Site(bp): 160285130 External Links: ENSG00000258465

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand DCAF8L1 chrX 27977992 27981449 - RAC1 chr7 6374527 6403967 + RPL11 chr1 23691742 23696835 + RRAGC chr1 38838198 38859772 - PPIL3 chr2 200870907 200889303 - FAM210A chr18 13663347 13726663 - RLIM chrX 74582976 74614624 - NPM1 chr5 171387116 171411137 + SEC61A1 chr3 128051641 128071683 + WDR6 chr3 49007062 49015953 + HLA-DRB1 chr6 32578769 32589848 - KNOP1 chr16 19701937 19718235 - RPL15 chr3 23916545 23924374 + RAB8A chr19 16111889 16134234 + COX6A1 chr12 120438090 120440737 + CBX2 chr17 79778148 79787983 + MAPKAP1 chr9 125437393 125707234 - GAPDH chr12 6534512 6538374 + EIF4B chr12 53006158 53042209 + NUP85 chr17 75205659 75235758 + ST13 chr22 40824535 40856639 - GPR153 chr1 6247353 6261098 - PRPS2 chrX 12791355 12824222 + MDK chr11 46380756 46383837 + DCAF8 chr1 160215715 160262549 - LITAF chr16 11547722 11636381 - BCL2L1 chr20 31664452 31723989 - U2AF2 chr19 55654146 55674715 + SLC12A2 chr5 128083766 128189677 + PPP1R1B chr17 39626740 39636626 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-142-3p chr17 58331245 58331267 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004687.1 chr17 58330884 58332508 - SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.