exRNAdisease

Entry Detail

---



General Information

Database ID: exR0755591 RNA Name: AL139353.1 RNA Type: mRNA Chromosome: chr14 Starnd: - Coordinate: Start Site(bp): 31334312 End Site(bp): 31457441 External Links: ENSG00000203546

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AP002990.1 chr11 62559603 62591531 - BBS5 chr2 169479480 169506655 + BSG chr19 571277 583493 + DNAJA3 chr16 4425805 4456775 + DTD2 chr14 31446036 31457506 - EEF1G chr11 62559596 62574086 - EIF3L chr22 37848868 37889407 + HEATR5A chr14 31291788 31420550 - IRS4 chrX 108732482 108736409 - LCAT chr16 67939750 67944131 - LDHA chr11 18394560 18408425 + LSM4 chr19 18306230 18323274 - NAP1L1 chr12 76036585 76084958 - PMPCA chr9 136410641 136423761 + PTPRF chr1 43525187 43623666 + RPL13 chr16 89560657 89566828 + RPS29 chr14 49570984 49599164 - SUPT5H chr19 39436156 39476670 + TMBIM6 chr12 49707725 49764934 + TNFRSF14 chr1 2555639 2565382 + UFM1 chr13 38349849 38363619 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand XIST chrX 73820649 73852723 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.