exRNAdisease

Entry Detail

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General Information

Database ID: exR0755926 RNA Name: ARPP19 RNA Type: mRNA Chromosome: chr15 Starnd: - Coordinate: Start Site(bp): 52547045 End Site(bp): 52569883 External Links: ENSG00000128989

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD1 chrX 153724856 153744755 + ABL2 chr1 179099330 179229684 - AC010422.3 chr19 12643831 12648397 - ACAT2 chr6 159762045 159779112 + ACTG1 chr17 81509971 81523847 - AHCYL2 chr7 129225023 129430211 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-24-3p chr9 95086064 95086085 + hsa-miR-105-5p chrX 152394458 152394480 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-135a-5p chr12 97563834 97563856 + hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-323a-3p chr14 101025782 101025802 + hsa-miR-135b-5p chr1 205448361 205448383 - hsa-miR-3654 chr7 133034860 133034878 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC078881.1 chr4 177442519 177681381 + AC132217.1 chr11 2129121 2129964 - AL137230.2 chr14 89628921 89642671 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.