exRNAdisease

Entry Detail

---



General Information

Database ID: exR0756014 RNA Name: ATP1A1 RNA Type: mRNA Chromosome: chr1 Starnd: + Coordinate: Start Site(bp): 116372668 End Site(bp): 116410261 External Links: ENSG00000163399

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC005943.1 chr19 1578339 1605445 - AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC012254.2 chr18 47108188 47176345 - AC027644.4 chr7 66628958 66811189 + AC105052.1 chr7 102582523 102642869 - AC110275.1 chr8 43018424 43077334 + AC120057.2 chr17 7240427 7244635 - AC139530.2 chr17 81703371 81720539 + ACKR3 chr2 236567787 236582354 + ACTC1 chr15 34790230 34795549 - ACTG1 chr17 81509971 81523847 - ADCY3 chr2 24819169 24919839 - AHDC1 chr1 27534035 27604431 - AK3 chr9 4709556 4742043 - AK9 chr6 109492856 109691217 - AKR7A2 chr1 19303965 19312146 - AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-5100 chr10 42997630 42997651 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC051619.6 chr15 45198517 45199139 - AC067930.1 chr8 143579636 143580670 + AC129492.1 chr17 8079482 8081565 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL118558.3 chr14 101948347 101949425 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.