exRNAdisease

Entry Detail

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General Information

Database ID: exR0756498 RNA Name: CALM1 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 90396502 End Site(bp): 90408268 External Links: ENSG00000198668

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - AC008758.1 chr19 12461559 12551474 - AC010422.3 chr19 12643831 12648397 - ACACB chr12 109116595 109268226 + ACTB chr7 5527148 5563784 - ACTL6A chr3 179562886 179588407 + ACTR2 chr2 65227753 65271253 + ADCY6 chr12 48766194 48789037 - ADNP chr20 50888916 50931437 - AFG3L2 chr18 12328944 12377227 - AGO1 chr1 35869808 35930532 + AGPAT1 chr6 32168212 32178096 - AHCY chr20 34280268 34311802 - AKAP12 chr6 151239967 151358559 + AL117348.2 chr1 225886696 225924278 - AL136531.2 chr20 1317571 1393096 - AL365205.1 chr6 41780349 41790141 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-206 chr6 52144401 52144422 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-660-5p chrX 50013256 50013277 + hsa-miR-362-3p chrX 50009005 50009026 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004812.2 chr12 120116907 120119000 + AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.