Entry Detail


General Information

Database ID:exR0756731
RNA Name:CCT2
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):69585426End Site(bp):69601570
External Links:ENSG00000166226



Disease Information

Disease Name:Glioblastoma Multiforme
Disease Category:Cancers
MeSH ID:D005909
Type:Neoplasms/Neoplasms, Glandular and Epithelial
Alias:Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell



Expression Detail

GEO ID:GSE106804
Description:Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles
Experimental Design:Cancer vs Control
Case Disease Type:Glioblastoma Multiforme
Case Disease SubType:NA
Case Sample:Glioblastoma Multiforme
Control Sample:Healthy
Number of Case:13
Number of Control:6
Number of Samples:19





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
ABI2
chr2
203328239
203447728
+
AC104452.1
chr3
49416777
49429314
-
AC120057.2
chr17
7240427
7244635
-
AC124312.1
chr15
24955034
25000276
+
AC138811.2
chr16
18788063
18801519
-
ACER3
chr11
76860867
77026797
+
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTR1A
chr10
102461881
102502712
-
ADNP
chr20
50888916
50931437
-
AGGF1
chr5
77029251
77065234
+
AKIRIN1
chr1
38991276
39006059
+
AL049629.2
chr11
33698261
33722467
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1244
chr2
231713368
231713393
+
hsa-miR-3609
chr7
98881700
98881723
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC005899.4
chr17
32328441
32329395
+
AD000090.1
chr19
35557956
35581954
+
AL049543.1
chr6
28587378
28591747
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:29330365
Title:Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles.
Author:Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL.
Journal:Nat Commun. 2018 Jan 12;9(1):175.
Description:Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.