exRNAdisease

Entry Detail

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General Information

Database ID: exR0756734 RNA Name: CCT5 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 10249929 End Site(bp): 10266389 External Links: ENSG00000150753

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010422.5 chr19 12664828 12669397 - AC010463.1 chr19 17267418 17282966 + AC091167.2 chr15 90249556 90272208 + AC137834.1 chr12 57249609 57296484 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAM17 chr2 9488486 9556732 - ADD2 chr2 70607618 70768225 - ADGRL2 chr1 81306160 81992436 + ADH5 chr4 99070978 99088801 - ADNP chr20 50888916 50931437 - AGPAT1 chr6 32168212 32178096 - AGRN chr1 1020120 1056118 + AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKIRIN1 chr1 38991276 39006059 + AKT1S1 chr19 49869033 49878459 - AL121594.1 chr14 35122549 35317474 + AL133352.1 chr10 100505628 100529881 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302c-3p chr4 112648366 112648388 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008649.1 chr19 38596346 38601694 + AC009831.1 chr18 31942575 31944156 + AC069281.2 chr7 100572232 100578700 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.