exRNAdisease

Entry Detail

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General Information

Database ID: exR0757106 RNA Name: CLIC1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31730581 End Site(bp): 31739763 External Links: ENSG00000213719

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC006030.1 chr2 74211604 74363377 - AC008763.3 chr19 7678501 7682854 + AC010132.3 chr7 42909273 42932174 - AC011448.1 chr19 19516227 19536076 + AC012184.2 chr16 70299194 70372582 + AC107959.5 chr8 23084403 23115536 + ACIN1 chr14 23058564 23095614 - ACTB chr7 5527148 5563784 - AD000671.2 chr19 35739252 35745432 - AGPAT4 chr6 161129967 161274061 - AHNAK chr11 62433542 62556235 - AKT1 chr14 104769349 104795751 - AL133352.1 chr10 100505628 100529881 - ALAS1 chr3 52198086 52214327 + ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-7703 chr14 24143489 24143511 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010325.2 chr19 50792685 50793584 - AC107959.4 chr8 23084355 23103558 + AC245014.3 chr1 145281116 145281462 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.