exRNAdisease

Entry Detail

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General Information

Database ID: exR0757295 RNA Name: COTL1 RNA Type: mRNA Chromosome: chr16 Starnd: - Coordinate: Start Site(bp): 84565596 End Site(bp): 84618078 External Links: ENSG00000103187

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004922.1 chr7 99325879 99394653 + AC008982.1 chr19 38817471 38840178 - AC068580.4 chr11 1734821 1763954 - AC073508.2 chr17 40627356 40665141 - AC092143.1 chr16 89919165 89936092 + AC124312.1 chr15 24955034 25000276 + ACAA1 chr3 38103129 38137242 - ACAA2 chr18 49782164 49813953 - ACP1 chr2 264140 278283 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADRM1 chr20 62302093 62308862 + AHCY chr20 34280268 34311802 - AKR1A1 chr1 45550543 45570049 + AKR1B1 chr7 134442356 134459284 - AKT1 chr14 104769349 104795751 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004951.4 chr7 43951910 44019151 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.