exRNAdisease

Entry Detail

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General Information

Database ID: exR0757397 RNA Name: CS RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 56271699 End Site(bp): 56300391 External Links: ENSG00000062485

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCB9 chr12 122920951 122981649 - ABHD10 chr3 111979010 111993368 + AC004922.1 chr7 99325879 99394653 + AC073896.1 chr12 56285916 56316059 - AC138811.2 chr16 18788063 18801519 - ACTR2 chr2 65227753 65271253 + AHCYL1 chr1 109984765 110023742 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-196a-5p chr17 48632532 48632553 - hsa-miR-196b-5p chr7 27169528 27169549 - hsa-miR-431-5p chr14 100881026 100881046 + hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-198 chr3 120395703 120395724 - hsa-miR-5001-5p chr2 232550530 232550553 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC008267.5 chr7 66493607 66495758 + AC040977.2 chr17 6985494 7019414 - AC115284.1 chr3 51961212 51974031 - AL031595.3 chr22 44139365 44153626 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.