exRNAdisease

Entry Detail

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General Information

Database ID: exR0757449 RNA Name: CTNNA1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 138610967 End Site(bp): 138935034 External Links: ENSG00000044115

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAK1 chr2 69457997 69674349 - AAMP chr2 218264123 218270257 - AC011455.2 chr19 38915404 38949855 - AC099811.2 chr17 42119674 42154916 - ACIN1 chr14 23058564 23095614 - ACSL3 chr2 222860942 222944639 + ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ADA2 chr22 17178790 17258235 - ADARB1 chr21 45073853 45226560 + ADD3 chr10 109996368 110135565 + ADH5 chr4 99070978 99088801 - ADNP chr20 50888916 50931437 - ADNP2 chr18 80109262 80147523 + ADSL chr22 40346500 40390463 + AGPAT1 chr6 32168212 32178096 - AIG1 chr6 143060496 143341058 + AKAP8 chr19 15353385 15379798 - AL022238.4 chr22 40346529 40410054 + AL603832.3 chr1 112702614 112711433 - ALDH16A1 chr19 49453225 49471050 + ALDH2 chr12 111766887 111817532 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-320a-3p chr8 22244975 22244996 - hsa-miR-7705 chr8 100703002 100703024 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007405.3 chr2 170814686 170818037 - AC018521.1 chr17 47945424 47981736 + AC026304.1 chr3 143000907 143001467 - AC092490.1 chr12 8788253 8795789 + AC138035.1 chr5 181306502 181324685 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.