exRNAdisease

Entry Detail

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General Information

Database ID: exR0757637 RNA Name: DDB1 RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 61299451 End Site(bp): 61342596 External Links: ENSG00000167986

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABCB8 chr7 151028422 151047782 + ABI2 chr2 203328239 203447728 + ABRACL chr6 139028745 139043302 + AC005258.1 chr19 2269525 2341172 + AC008982.1 chr19 38817471 38840178 - AC011448.1 chr19 19516227 19536076 + AC118549.1 chr1 77562416 77683419 - ACBD6 chr1 180269653 180502954 - ACIN1 chr14 23058564 23095614 - ACSL1 chr4 184755595 184826818 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ACTR8 chr3 53867066 53882152 - ADAMTS1 chr21 26835755 26845409 - ADAR chr1 154582057 154628013 - ADGRG6 chr6 142301854 142446266 + AGO2 chr8 140520156 140635633 - AGPAT4 chr6 161129967 161274061 - AJUBA chr14 22971177 22982551 - AKR7A2 chr1 19303965 19312146 - AKT1 chr14 104769349 104795751 - AKT1S1 chr19 49869033 49878459 - AL133352.1 chr10 100505628 100529881 - AL136454.1 chr1 192716132 192716653 + AL139011.2 chr1 160216800 160285130 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-155-3p chr21 25574022 25574043 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012485.1 chr2 238231684 238255633 + AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC124068.2 chr15 89335053 89336161 + AC133644.3 chr2 87455476 87767359 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.