exRNAdisease

Entry Detail

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General Information

Database ID: exR0757646 RNA Name: DDOST RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 20651767 End Site(bp): 20661544 External Links: ENSG00000244038

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + ABHD14B chr3 51968510 51983409 - ABO chr9 133250401 133276024 - AC007192.1 chr19 18153158 18178117 + AC024592.3 chr19 5866171 5903787 - AC104452.1 chr3 49416777 49429314 - AC104581.2 chr17 7925931 7930622 - AC118549.1 chr1 77562416 77683419 - ACACA chr17 37084992 37406836 - ACAP3 chr1 1292390 1309609 - ACTG1 chr17 81509971 81523847 - ADAM23 chr2 206443532 206621127 + ADAMTS19 chr5 129460281 129738683 + ADD3 chr10 109996368 110135565 + ADSL chr22 40346500 40390463 + AGFG1 chr2 227472152 227561214 + AGPAT5 chr8 6708642 6761503 + AHCYL2 chr7 129225023 129430211 + AL022238.4 chr22 40346529 40410054 + AL121594.1 chr14 35122549 35317474 + AL136295.4 chr14 24180395 24190416 - ALDH1B1 chr9 38392702 38398661 + ALDH9A1 chr1 165662216 165698863 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC092490.1 chr12 8788253 8795789 + AC106864.1 chr4 112693047 112706810 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.