exRNAdisease

Entry Detail

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General Information

Database ID: exR0757674 RNA Name: DDX5 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 64498254 End Site(bp): 64508199 External Links: ENSG00000108654

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB4 chr7 87401697 87480435 - ABCB7 chrX 75051048 75156732 - ABCF2 chr7 151207837 151227166 - AC005258.1 chr19 2269525 2341172 + AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC024592.3 chr19 5866171 5903787 - AC048338.1 chr12 122207779 122266423 - AC093525.2 chr16 2496032 2520218 + AC120057.2 chr17 7240427 7244635 - AC245033.1 chr15 82536788 82573194 - ACOT13 chr6 24667035 24705065 + ACSS2 chr20 34872146 34927962 + ADA2 chr22 17178790 17258235 - ADIPOR2 chr12 1688574 1788674 + AFDN chr6 167826922 167972023 + AGFG2 chr7 100539203 100568220 + AGO1 chr1 35869808 35930532 + AGO4 chr1 35808016 35857890 + AGPAT5 chr8 6708642 6761503 + AHDC1 chr1 27534035 27604431 - AKAP12 chr6 151239967 151358559 + AKIRIN1 chr1 38991276 39006059 + AL133352.1 chr10 100505628 100529881 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-33a-5p chr22 41900949 41900969 + hsa-miR-141-3p chr12 6964155 6964176 + hsa-miR-206 chr6 52144401 52144422 + hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-33b-5p chr17 17813897 17813916 - hsa-miR-3064-5p chr17 64500817 64500837 - hsa-miR-3064-3p chr17 64500775 64500797 - hsa-miR-5047 chr17 64501230 64501250 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC079781.5 chr7 97851688 97972985 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.