exRNAdisease

Entry Detail

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General Information

Database ID: exR0757966 RNA Name: DYNC1H1 RNA Type: mRNA Chromosome: chr14 Starnd: + Coordinate: Start Site(bp): 101964573 End Site(bp): 102056443 External Links: ENSG00000197102

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + AC090004.1 chr3 14135217 14148252 + AC093525.1 chr16 2513965 2527955 + AC093525.2 chr16 2496032 2520218 + AC104109.3 chr5 134167170 134226071 - AC138969.1 chr16 16317444 16350590 + AC245033.1 chr15 82536788 82573194 - ACAA2 chr18 49782164 49813953 - ADAMTS15 chr11 130448974 130476641 + ADCY3 chr2 24819169 24919839 - ADD2 chr2 70607618 70768225 - AGRN chr1 1020120 1056118 + AIF1L chr9 131096476 131123152 + AK3 chr9 4709556 4742043 - AKAP1 chr17 57085092 57121346 + AL139300.1 chr14 103562962 103685924 + AL162417.1 chr9 133098121 133163914 - ALDH18A1 chr10 95605941 95656711 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC008124.1 chr12 45718046 45727775 - AC110285.2 chr17 81388126 81390319 - AC245014.3 chr1 145281116 145281462 + AL022157.1 chrX 57121662 57127243 + AL110115.2 chr20 31580890 31581214 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.