exRNAdisease

Entry Detail

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General Information

Database ID: exR0758021 RNA Name: EEF1B2 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 206159585 End Site(bp): 206162928 External Links: ENSG00000114942

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD8 chr19 17292131 17310236 - ABI2 chr2 203328239 203447728 + AC005258.1 chr19 2269525 2341172 + AC006978.2 chr7 30362400 30412502 + AC007192.1 chr19 18153158 18178117 + AC008763.3 chr19 7678501 7682854 + AC009133.6 chr16 29812261 29820092 + AC099811.2 chr17 42119674 42154916 - AC118553.2 chr1 99970011 100083321 + AC139530.2 chr17 81703371 81720539 + ACAP3 chr1 1292390 1309609 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTG2 chr2 73892314 73919865 + ACTN4 chr19 38647649 38731589 + ACTR1A chr10 102461881 102502712 - ACTR2 chr2 65227753 65271253 + ACTR3 chr2 113890063 113962596 + ADAM8 chr10 133262420 133276868 - ADSL chr22 40346500 40390463 + AHDC1 chr1 27534035 27604431 - AHSA1 chr14 77457870 77469472 + AIMP1 chr4 106315544 106349456 + AK2 chr1 33007940 33080996 - AL049629.2 chr11 33698261 33722467 - ALDH4A1 chr1 18871430 18902724 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-21-5p chr17 59841273 59841294 + hsa-miR-6892-5p chr7 143382686 143382706 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004477.1 chr17 48045141 48048073 - AC007952.4 chr17 19112000 19112636 - AC017100.1 chr18 31685655 31686823 + AC105339.2 chr15 82752884 82757208 + AL022311.1 chr22 37876148 37895563 + AL132655.2 chr20 58817132 58817725 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.