exRNAdisease

Entry Detail

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General Information

Database ID: exR0758092 RNA Name: EIF3E RNA Type: mRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 108201216 End Site(bp): 108435333 External Links: ENSG00000104408

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC008764.4 chr19 16577642 16660115 - AC009133.6 chr16 29812261 29820092 + AC012184.2 chr16 70299194 70372582 + AC048338.1 chr12 122207779 122266423 - AC079447.1 chr2 99141485 99322741 + AC092587.1 chr2 99154998 99195298 + AC104452.1 chr3 49416777 49429314 - AC120057.2 chr17 7240427 7244635 - ACTB chr7 5527148 5563784 - ADK chr10 74151202 74709963 + AHCY chr20 34280268 34311802 - AL136454.1 chr1 192716132 192716653 + ALCAM chr3 105366909 105576900 + ALDH1B1 chr9 38392702 38398661 + ALDH5A1 chr6 24494867 24537207 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-4284 chr7 73711327 73711344 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010618.3 chr19 17488990 17511889 - AC021078.1 chr5 149494314 149504670 - AC124312.5 chr15 25091786 25107469 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.