exRNAdisease

Entry Detail

---



General Information

Database ID: exR0758103 RNA Name: EIF4B RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 53006158 End Site(bp): 53042209 External Links: ENSG00000063046

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABLIM1 chr10 114431113 114768061 - AC008763.3 chr19 7678501 7682854 + AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC058822.1 chr4 53377839 54295272 + AC073508.2 chr17 40627356 40665141 - AC093525.1 chr16 2513965 2527955 + AC124312.1 chr15 24955034 25000276 + AC245033.1 chr15 82536788 82573194 - ACADVL chr17 7217125 7225266 + ACOT8 chr20 45841721 45857405 - ACSF2 chr17 50426158 50474845 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACVR1 chr2 157736444 157876330 - ADAL chr15 43330657 43354555 + ADAR chr1 154582057 154628013 - ADIPOR2 chr12 1688574 1788674 + ADORA2A chr22 24417879 24442357 + AEN chr15 88621337 88632281 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AIG1 chr6 143060496 143341058 + AIMP1 chr4 106315544 106349456 + AKNA chr9 114334156 114394405 - AL121594.1 chr14 35122549 35317474 + AL139011.2 chr1 160216800 160285130 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3680-5p chr16 21506101 21506122 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC018647.2 chr7 35695214 35699413 + AC023509.1 chr12 53441741 53467528 + AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + AL118506.1 chr20 63861212 63864293 - AL121832.3 chr20 62402236 62405935 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.