exRNAdisease

Entry Detail

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General Information

Database ID: exR0758111 RNA Name: EIF4H RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 74174245 End Site(bp): 74197101 External Links: ENSG00000106682

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABCF2 chr7 151207837 151227166 - AC010422.3 chr19 12643831 12648397 - AC023055.1 chr12 55757275 55827546 - AC046185.1 chr17 63702845 63752097 - AC092647.5 chr7 55887277 55955239 + AC139530.2 chr17 81703371 81720539 + AC244197.3 chrX 149477104 149540926 - ACBD6 chr1 180269653 180502954 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ACTN4 chr19 38647649 38731589 + ADAMTSL4 chr1 150549369 150560937 + ADD3 chr10 109996368 110135565 + ADGRG2 chrX 18989307 19122637 - ADIPOR1 chr1 202940826 202958572 - ADRM1 chr20 62302093 62308862 + AHI1 chr6 135283532 135497765 - AHSA1 chr14 77457870 77469472 + AKIRIN1 chr1 38991276 39006059 + AL031708.1 chr16 1632259 1686715 + AL109827.1 chr20 35632340 35674544 - AL713999.1 chr1 155169409 155187272 - ALDH7A1 chr5 126531200 126595362 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4444 chr2 177212768 177212785 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC007218.1 chr16 9666885 9676843 - AC007878.1 chr2 71373938 71376320 + AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.