exRNAdisease

Entry Detail

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General Information

Database ID: exR0758325 RNA Name: EZR RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 158765741 End Site(bp): 158819368 External Links: ENSG00000092820

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABRACL chr6 139028745 139043302 + AC004922.1 chr7 99325879 99394653 + AC010132.3 chr7 42909273 42932174 - AC092143.1 chr16 89919165 89936092 + AC245033.1 chr15 82536788 82573194 - ACAT1 chr11 108116695 108147603 + ACKR3 chr2 236567787 236582354 + ACTB chr7 5527148 5563784 - ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ADH5 chr4 99070978 99088801 - ADIPOR1 chr1 202940826 202958572 - ADSL chr22 40346500 40390463 + AFDN chr6 167826922 167972023 + AGBL5 chr2 27042364 27070622 + AGPAT2 chr9 136673143 136687457 - AL022238.4 chr22 40346529 40410054 + AL136295.4 chr14 24180395 24190416 - AL365205.1 chr6 41780349 41790141 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010733.2 chr2 60925909 60931610 + AC023509.1 chr12 53441741 53467528 + AC106864.1 chr4 112693047 112706810 - AC110619.1 chr2 240449315 240456714 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.