exRNAdisease

Entry Detail

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General Information

Database ID: exR0758475 RNA Name: FAU RNA Type: mRNA Chromosome: chr11 Starnd: - Coordinate: Start Site(bp): 65120630 End Site(bp): 65122177 External Links: ENSG00000149806

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA2 chr9 137007234 137028922 - ABCB9 chr12 122920951 122981649 - ABHD12 chr20 25294742 25390835 - AC007192.1 chr19 18153158 18178117 + AC008982.1 chr19 38817471 38840178 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC114490.2 chr1 34981533 35031741 - AC135050.2 chr16 31083439 31094956 - ACAD9 chr3 128879596 128916067 + ACAT2 chr6 159762045 159779112 + ACIN1 chr14 23058564 23095614 - ACSS1 chr20 25006230 25058980 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN1 chr14 68874143 68979440 - ACTN4 chr19 38647649 38731589 + ADH5 chr4 99070978 99088801 - ADM chr11 10305073 10307397 + ADPRM chr17 10697594 10711558 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AL031708.1 chr16 1632259 1686715 + AL133352.1 chr10 100505628 100529881 - AL138752.2 chr9 37588413 38068687 - AL162377.3 chr13 51763951 51845159 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4485-3p chr11 10508277 10508296 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC009022.1 chr16 69976297 70065948 - AC010642.2 chr19 58309727 58327248 - AC139149.1 chr17 81514047 81527776 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.