exRNAdisease

Entry Detail

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General Information

Database ID: exR0758612 RNA Name: FKBP8 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 18531751 End Site(bp): 18544077 External Links: ENSG00000105701

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCA5 chr17 69244311 69327244 - ABCC4 chr13 95019835 95301475 - ABR chr17 1003518 1229738 - AC007192.1 chr19 18153158 18178117 + AC008878.3 chr19 7382834 7470241 + AC010132.3 chr7 42909273 42932174 - AC012184.2 chr16 70299194 70372582 + AC024592.3 chr19 5866171 5903787 - AC055811.2 chr17 17202649 17237185 - AC073896.1 chr12 56285916 56316059 - AC138811.2 chr16 18788063 18801519 - ACAT2 chr6 159762045 159779112 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ADCK5 chr8 144373101 144393242 + ADGRE2 chr19 14732392 14778560 - ADGRL1 chr19 14147743 14206187 - ADO chr10 62804720 62808479 + AEN chr15 88621337 88632281 + AFDN chr6 167826922 167972023 + AGPAT3 chr21 43865223 43987592 + AHCTF1 chr1 246839098 246931967 - AIFM1 chrX 130129362 130165887 - AKAP10 chr17 19904302 19978343 - AKNA chr9 114334156 114394405 - AL365205.1 chr6 41780349 41790141 + AL603832.3 chr1 112702614 112711433 - ALCAM chr3 105366909 105576900 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-3652 chr12 103930425 103930442 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC010615.2 chr19 21444241 21463908 - AC026362.1 chr12 122975320 122982907 + AC069281.2 chr7 100572232 100578700 - AC074183.1 chr7 84939349 84940245 - AC099778.1 chr3 47379089 47380999 - AC106864.1 chr4 112693047 112706810 - AC109460.3 chr16 28974804 28990775 + AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC245014.3 chr1 145281116 145281462 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.