exRNAdisease

Entry Detail

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General Information

Database ID: exR0758706 RNA Name: FTL RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 48965309 End Site(bp): 48966879 External Links: ENSG00000087086

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC027644.4 chr7 66628958 66811189 + AC093525.2 chr16 2496032 2520218 + AAGAB chr15 67200667 67255195 - AL136454.1 chr1 192716132 192716653 + AC004922.1 chr7 99325879 99394653 + AGPAT2 chr9 136673143 136687457 - AC018523.2 chr11 14493783 14520344 - AKIRIN2 chr6 87674860 87702233 - AC008763.3 chr19 7678501 7682854 + AK4 chr1 65147549 65232145 + ACLY chr17 41866917 41930542 - AC138969.1 chr16 16317444 16350590 + ADPRH chr3 119579268 119589945 + AC004997.1 chr22 30285238 30299482 - AC069503.2 chr12 121888809 121921470 + AKAP8L chr19 15380050 15419141 - ACTR3 chr2 113890063 113962596 + AC005258.1 chr19 2269525 2341172 + ALDH3A2 chr17 19648136 19685760 + AIP chr11 67483026 67491103 + AIF1L chr9 131096476 131123152 + AIFM2 chr10 70098223 70132934 - ACBD6 chr1 180269653 180502954 - ACTB chr7 5527148 5563784 - ACTR8 chr3 53867066 53882152 - ABHD8 chr19 17292131 17310236 - AC105052.3 chr7 102637049 102671641 - ACP1 chr2 264140 278283 + ADGRA3 chr4 22345071 22516066 - ADD3 chr10 109996368 110135565 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-639 chr19 14529603 14529625 + hsa-miR-4426 chr1 192716333 192716349 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002467.1 chr7 107739999 107744581 - AC004687.1 chr17 58330884 58332508 - AC005696.1 chr17 2712309 2712833 + AC006504.5 chr19 27793431 27984984 + AC007114.1 chr17 57071814 57085024 - AC007952.4 chr17 19112000 19112636 - AC009908.1 chr8 124996985 124998198 - AC010327.5 chr19 55216660 55221616 + AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AC026362.1 chr12 122975320 122982907 + AC079174.2 chr12 106250759 106252786 + AC118553.1 chr1 99968383 99969864 - AD000090.1 chr19 35557956 35581954 + AL022157.1 chrX 57121662 57127243 + AL022311.1 chr22 37876148 37895563 + AL033527.3 chr1 39788976 39790171 + AL137230.2 chr14 89628921 89642671 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.