exRNAdisease

Entry Detail

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General Information

Database ID: exR0759019 RNA Name: GPI RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 34359480 End Site(bp): 34402413 External Links: ENSG00000105220

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASDHPPT chr11 106075501 106098699 + ABLIM1 chr10 114431113 114768061 - AC007040.2 chr2 70939318 70995336 - AC008764.4 chr19 16577642 16660115 - AC010132.3 chr7 42909273 42932174 - AC010323.1 chr19 8308283 8321379 - AC010422.3 chr19 12643831 12648397 - AC092073.1 chr19 34396315 34409364 + AC137834.1 chr12 57249609 57296484 - AC245033.1 chr15 82536788 82573194 - ACSS1 chr20 25006230 25058980 - ACTA1 chr1 229431245 229434098 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ADAMTS1 chr21 26835755 26845409 - ADO chr10 62804720 62808479 + AHCY chr20 34280268 34311802 - AIP chr11 67483026 67491103 + AL138752.2 chr9 37588413 38068687 - ALDH7A1 chr5 126531200 126595362 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-7106-3p chr12 113159113 113159135 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC010655.2 chr7 128455937 128469197 + AC010655.4 chr7 128455840 128493859 + AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC091564.7 chr11 6610883 6616594 - AC104971.3 chr18 58659858 58660524 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL096870.2 chr14 24209646 24215987 - AL136419.1 chr14 23969931 24051377 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.