exRNAdisease

Entry Detail

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General Information

Database ID: exR0759219 RNA Name: HDGF RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 156742109 End Site(bp): 156766925 External Links: ENSG00000143321

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABL1 chr9 130713016 130887675 + AC006030.1 chr2 74211604 74363377 - AC006064.6 chr12 6556886 6607367 - AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC093525.2 chr16 2496032 2520218 + AC124312.1 chr15 24955034 25000276 + AC139530.2 chr17 81703371 81720539 + ACTB chr7 5527148 5563784 - ADAR chr1 154582057 154628013 - ADD2 chr2 70607618 70768225 - ADD3 chr10 109996368 110135565 + ADNP chr20 50888916 50931437 - AHCYL1 chr1 109984765 110023742 + AIF1L chr9 131096476 131123152 + AKIRIN2 chr6 87674860 87702233 - AKR1A1 chr1 45550543 45570049 + AL136454.1 chr1 192716132 192716653 + AL139011.2 chr1 160216800 160285130 - AL590132.1 chr1 210858125 211134146 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-15b-5p chr3 160404607 160404628 + hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-873-5p chr9 28888925 28888945 - hsa-miR-1286 chr22 20249145 20249165 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005083.1 chr7 20217577 20221700 + AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AC026362.1 chr12 122975320 122982907 + AC069281.2 chr7 100572232 100578700 - AC079781.5 chr7 97851688 97972985 - AC105036.3 chr15 75527150 75601205 - AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.