exRNAdisease

Entry Detail

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General Information

Database ID: exR0759224 RNA Name: HDLBP RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 241227264 End Site(bp): 241317061 External Links: ENSG00000115677

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAK1 chr2 69457997 69674349 - AASS chr7 122073549 122144255 - AC002985.1 chr19 18907013 18934397 - AC004922.1 chr7 99325879 99394653 + AC011462.1 chr19 41350853 41425001 + AC097637.1 chr3 52221081 52231190 - ACACB chr12 109116595 109268226 + ACAD9 chr3 128879596 128916067 + ACAT2 chr6 159762045 159779112 + ACIN1 chr14 23058564 23095614 - ACTR1B chr2 97655939 97664044 - ADH5 chr4 99070978 99088801 - AHCY chr20 34280268 34311802 - AIMP2 chr7 6009255 6023834 + AK3 chr9 4709556 4742043 - AKR1A1 chr1 45550543 45570049 + AKT2 chr19 40230317 40285536 - AL138752.2 chr9 37588413 38068687 - AL355987.3 chr9 136791379 136800595 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7d-5p chr9 94178841 94178862 + hsa-let-7e-5p chr19 51692793 51692814 + hsa-let-7f-5p chrX 53557246 53557267 - hsa-miR-214-3p chr1 172138816 172138837 - hsa-let-7g-5p chr3 52268336 52268357 - hsa-let-7i-5p chr12 62603691 62603712 + hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-629-5p chr15 70079427 70079447 - hsa-miR-1321 chrX 85835832 85835849 + hsa-miR-3652 chr12 103930425 103930442 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.