exRNAdisease

Entry Detail

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General Information

Database ID: exR0759272 RNA Name: HIF1AN RNA Type: mRNA Chromosome: chr10 Starnd: + Coordinate: Start Site(bp): 100529072 End Site(bp): 100559998 External Links: ENSG00000166135

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006978.2 chr7 30362400 30412502 + AC118553.2 chr1 99970011 100083321 + ADAM15 chr1 155050566 155062775 + ADAR chr1 154582057 154628013 - AL021546.1 chr12 120438198 120460006 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-18a-5p chr13 91350756 91350778 + hsa-miR-199a-5p chr1 172144592 172144614 - hsa-miR-138-5p chr16 56858527 56858549 + hsa-miR-516b-5p chr19 53736860 53736881 + hsa-miR-493-3p chr14 100869116 100869137 + hsa-miR-642a-5p chr19 45674943 45674964 + hsa-miR-650 chr22 22822791 22822811 + hsa-miR-663a chr20 26208243 26208264 - hsa-miR-362-3p chrX 50009005 50009026 + hsa-miR-1224-5p chr3 184241405 184241423 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.