exRNAdisease

Entry Detail

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General Information

Database ID: exR0759292 RNA Name: HLA-A RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 29941260 End Site(bp): 29945884 External Links: ENSG00000206503

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACHE chr7 100889994 100896974 - ACTR3 chr2 113890063 113962596 + ABCD1 chrX 153724856 153744755 + AGGF1 chr5 77029251 77065234 + ABHD2 chr15 89087459 89202355 + AC005258.1 chr19 2269525 2341172 + AKR1A1 chr1 45550543 45570049 + ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTC1 chr15 34790230 34795549 - ADCY1 chr7 45574140 45723116 + AFG3L2 chr18 12328944 12377227 - AL162417.1 chr9 133098121 133163914 - ALDOA chr16 30064164 30070457 + AFTPH chr2 64524305 64593005 + AL807752.6 chr9 137031241 137040436 - AC092073.1 chr19 34396315 34409364 + AC004922.1 chr7 99325879 99394653 + AGPAT1 chr6 32168212 32178096 - AL022238.4 chr22 40346529 40410054 + AHCY chr20 34280268 34311802 - AC007192.1 chr19 18153158 18178117 + AHCYL1 chr1 109984765 110023742 + AL136295.5 chr14 24147548 24166452 + ACIN1 chr14 23058564 23095614 - AL136454.1 chr1 192716132 192716653 + AC120057.2 chr17 7240427 7244635 - AGO1 chr1 35869808 35930532 + AC027644.4 chr7 66628958 66811189 + AC068547.1 chr2 151802651 151973949 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4680-5p chr10 110898094 110898116 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC008443.1 chr5 181246507 181272167 + AC009686.2 chr8 80032724 80033300 - AC010327.5 chr19 55216660 55221616 + AC016876.2 chr17 7581964 7584086 - AC023509.1 chr12 53441741 53467528 + AC026362.1 chr12 122975320 122982907 + AC084824.5 chr12 32736930 32737660 - AC245884.11 chr19 54308915 54337168 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.