exRNAdisease

Entry Detail

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General Information

Database ID: exR0759293 RNA Name: HLA-B RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31269491 End Site(bp): 31357188 External Links: ENSG00000234745

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTA2 chr10 88935074 88991339 - ACTG1 chr17 81509971 81523847 - ADPRHL2 chr1 36088892 36093932 + AK4 chr1 65147549 65232145 + AC092647.5 chr7 55887277 55955239 + ADM chr11 10305073 10307397 + AHCY chr20 34280268 34311802 - ACTB chr7 5527148 5563784 - ABCC10 chr6 43427366 43450427 + ACOT7 chr1 6264269 6394391 - ADAR chr1 154582057 154628013 - AGTRAP chr1 11736084 11754802 + ADI1 chr2 3497366 3519531 - AK2 chr1 33007940 33080996 - ABLIM1 chr10 114431113 114768061 - AC069503.2 chr12 121888809 121921470 + AL109827.1 chr20 35632340 35674544 - AGAP3 chr7 151085831 151144436 + AC011462.1 chr19 41350853 41425001 + AC135050.2 chr16 31083439 31094956 - AC046185.1 chr17 63702845 63752097 - ADRM1 chr20 62302093 62308862 + AC010422.3 chr19 12643831 12648397 - AC005258.1 chr19 2269525 2341172 + ADGRG2 chrX 18989307 19122637 - ACTR3 chr2 113890063 113962596 + ADCY1 chr7 45574140 45723116 + ACTA1 chr1 229431245 229434098 - ACADSB chr10 123008979 123058290 + AICDA chr12 8602170 8612867 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-6891-5p chr6 31355297 31355315 - hsa-miR-6516-5p chr17 77089428 77089449 + hsa-miR-6516-3p chr17 77089469 77089490 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC006942.1 chr19 49808933 49809738 + AC019205.1 chr6 73263212 73301789 + AC023509.1 chr12 53441741 53467528 + AC067852.2 chr17 42552436 42554748 - AC091564.7 chr11 6610883 6616594 - AC093157.1 chr1 101025844 101090513 + AC134043.2 chr5 159209921 159248796 + AC139530.1 chr17 81701324 81703300 - AC147651.4 chr7 603185 608482 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.