exRNAdisease

Entry Detail

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General Information

Database ID: exR0759294 RNA Name: HLA-C RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31268749 End Site(bp): 31272130 External Links: ENSG00000204525

Disease Information

Disease Name: Glioblastoma Multiforme Disease Category: Cancers MeSH ID: D005909 Type: Neoplasms/Neoplasms, Glandular and Epithelial Alias: Glioblastoma//Glioblastomas//Astrocytoma, Grade IV//Astrocytomas, Grade IV//Grade IV Astrocytoma//Grade IV Astrocytomas//Glioblastoma Multiforme//Giant Cell Glioblastoma//Giant Cell Glioblastomas//Glioblastoma, Giant Cell//Glioblastomas, Giant Cell

Expression Detail

GEO ID: GSE106804 Description: Engineered Nanointerfaces for Microfluidic Isolation and Molecular Profiling of Tumor-specific Extracellular Vesicles Experimental Design: Cancer vs Control Case Disease Type: Glioblastoma Multiforme Case Disease SubType: NA Case Sample: Glioblastoma Multiforme Control Sample: Healthy Number of Case: 13 Number of Control: 6 Number of Samples: 19

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF1 chr6 30571393 30597179 + AC005258.1 chr19 2269525 2341172 + AC010323.1 chr19 8308283 8321379 - AC015813.2 chr17 57989038 58007246 - AC018523.2 chr11 14493783 14520344 - AC024592.3 chr19 5866171 5903787 - AC027644.4 chr7 66628958 66811189 + AC087289.3 chr17 75898645 75930129 - ACOT9 chrX 23701055 23766475 - ACSS2 chr20 34872146 34927962 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTL6A chr3 179562886 179588407 + ACTR6 chr12 100199122 100241865 + AD000671.1 chr19 35745678 35754519 + ADA chr20 44619522 44652233 - ADD1 chr4 2843857 2930076 + ADD3 chr10 109996368 110135565 + ADORA2A chr22 24417879 24442357 + AFF1 chr4 86935002 87141054 + AGPAT3 chr21 43865223 43987592 + AHRR chr5 271670 438291 + AIMP1 chr4 106315544 106349456 + AKR1A1 chr1 45550543 45570049 + AKT1S1 chr19 49869033 49878459 - AKT3 chr1 243488233 243851079 - AL110118.2 chr14 93184973 93218586 + AL133352.1 chr10 100505628 100529881 - AL136295.5 chr14 24147548 24166452 + AL928654.3 chr14 105487199 105492267 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6891-3p chr6 31355228 31355248 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC093512.1 chr16 30064306 30064825 - AC099329.1 chr3 42785087 42852428 - AD000090.1 chr19 35557956 35581954 + AF131216.4 chr8 11283481 11285068 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 29330365 Title: Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles. Author: Re¨¢tegui E, van der Vos KE, Lai CP, Zeinali M, Atai NA, Aldikacti B, Floyd FP Jr, H Khankhel A, Thapar V, Hochberg FH, Sequist LV, Nahed BV, S Carter B, Toner M, Balaj L, T Ting D, Breakefield XO, Stott SL. Journal: Nat Commun. 2018 Jan 12;9(1):175. Description: Tumor-derived EVs have the potential to be utilized as disease-specific biomarkers, and genes specific to GBM as well as transcripts that are hallmarks for the four genetic subtypes of the disease.